The antibiofilm effects of some Cistus spp. against pathogenic microorganisms

Recently, the potential antibacterial or antibiofilm effects of some plant species belonging to Cistus sp. have motivated investigation their use as herbal remedies. In this study, activities aqueous (dH2O) leaf extracts laurifolius L., C. creticus L. and salviifolius on pathogenic microorganisms with biofilm forming ability were investigated. Biofilm pathogen test evaluated by congo red agar method microtiter plate all tested confirmed producers. Staphylococcus aureus ATCC 25923, Pseudomonas aeruginosa 11778, S. 6538, P. 27853 12600 strong The highest concentration examined both showed inhibition eradication against microorganisms. particular, studied good effect, 6538 12600. MBIC50 values found 6.25 µg/ml laurifolius, 50 extracts. Also, extract ≥ 90% growth (MBIC90 = µg/ml). MBEC50 determined in was required induce (MBEC90) Our study revealed that could be candidates for drug discovery treat capable infectious diseases especially ability.